HLA-B Genotype
Also known as: HLA B
Use
The HLA-B Genotype test is intended for use in immunization and vaccination trials or as an aid in the clinical diagnosis of diseases strongly associated with the HLA-B locus. The test uses a sequence-specific oligonucleotide probe hybridization methodology to achieve medium to high-resolution typing of the HLA-B locus. It helps in detecting specific HLA-B alleles that may be associated with certain diseases.
Special Instructions
Not provided.
Limitations
This test is not sufficient for comprehensive HLA evaluation required for clinical hematopoietic stem cell transplantation. If fewer than two alleles are reported for a locus, the patient is likely homozygous. Rare diagnostic errors may occur due to primer or probe site mutations. Occasionally, the specific allele cannot be determined; the most likely allele assignment is made followed by a sequence of letters for other possible alleles. Users should refer to provided resources for interpretation of allele codes.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
No genes
Gene
LOINC Codes
- 13299-3 - HLA-B
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
3 mL
Container
Lavender (EDTA), Pink (K2EDTA), or Yellow (ACD Solution A or B)
Causes for Rejection
Specimens collected in green (sodium or lithium heparin) tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 1 week |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant