Human Immunodeficiency Virus 1 (HIV-1), Quantitative, Real-time PCR (Nongraphical) With Reflex to HIV-1 GenoSure® MG

Casandra

Casandra Test Code LC86255Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 550432CPT Code 87536

Human Immunodeficiency Virus 1 (HIV-1), Quantitative, Real-time PCR (Nongraphical) With Reflex to HIV-1 GenoSure® MG

Also known as: HIV-1 Plasma Viremia, HIV-1 RNA by Real-time PCR, Quantitative, Reflex to Genotype, Viral Load

Clinical Use

Order Test

Use

Detect and quantitate HIV-1 in plasma with reflex to genotype (at additional charge) if viral load is >500 copies/mL. GenoSure® MG test detects mutations in the HIV viral genes that encode the HIV protease and polymerase (reverse transcriptase). Mutations in these genes have been associated with resistance to antiretroviral drugs.

Special Instructions

This procedure is intended for one-time use only and does not provide serial monitoring. If serial monitoring is required, a different test (550422) should be ordered.

Limitations

The assay range for this test is between 20 to 10,000,000 copies/mL. It doesn't support serial monitoring, making it essential to order the specified alternative for ongoing monitoring needs.

Test Details

Methodology

PCR-based (Real-time PCR)

Biomarkers

No genes

Gene

HIV-1 RNA b PCR • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

20447-9

Result Codes

20447-9
29541-0
8251-1

Result Turnaround Time

5-13 days

Specimen

Plasma

Volume

6 mL

Minimum Volume

4 mL

Container

Screw-cap polypropylene frozen transport tube

Collection Instructions

Collect specimen in three lavender-top (EDTA) tubes or three PPT™ tubes. Do not use green-top (heparin) tubes. Centrifuge specimen within six hours of collection. Transfer plasma to one or more screw-cap polypropylene transport tube(s). Avoid 'snap-cap' or 'pop-top' tubes as they may result in specimen rejection. Immediately freeze specimen at -20°C. Ship specimens frozen. Do not place samples on dry ice until completely frozen.