Humoral Immunity Panel I
Also known as: HUMPAN I
Use
The Humoral Immunity Panel I aids in the diagnosis or monitoring of immune deficiency disorders. It evaluates the patient's humoral immune response by measuring immunoglobulin levels, including subclasses and specific antibody responses to pneumococcal serotypes. This test also assists in assessing the efficacy of pneumonia vaccines through pre- and post-vaccination comparison, providing insights into individual immune competence based on the response to specific vaccine serotypes.
Special Instructions
The test requires pre- and post-vaccination samples to adequately assess the humoral immune response. Prevaccination samples should be collected prior to vaccine administration, and postvaccination samples should be collected at least 4 weeks after vaccination. Testing of postvaccination samples alone will only provide general immune status.
Limitations
The test may not provide comprehensive information on immune status if only postvaccination samples are used. Individual immune responses vary based on age, past exposure, immunocompetence, and pneumococcal serotype exposure. The test results may not be cleared or approved by the FDA but are developed under CLIA standards for clinical purposes.
New York Approved
Methodology
Immunoassay (Multiplex Chemiluminescent Immunoassay)
Biomarkers
LOINC Codes
- 13227-4
- 2458-8
- 2465-3
- 2472-9
- 53935-3
- 2466-1
- 2467-9
- 2468-7
- 2469-5
- 85954-6
- 86107-0
- 86130-2
- 27118-9
- 86080-9
- 25296-5
- 86169-0
- 85991-8
- 30153-1
- 85977-7
- 27395-3
- 86024-7
- 86064-3
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
5.5 mL
Minimum Volume
2.5 mL
Container
Serum separator tube
Collection Instructions
Separate serum from cells as soon as possible or within 2 hours of collection.
Causes for Rejection
Plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 14 days |
| Frozen | 60 days |
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