Iodine, 24 Hour, Urine
Use
Measurement of urinary iodine excretion in a 24‑hour urine collection is useful for assessing iodine toxicity or recent exposure and for monitoring iodine excretion rate as an index of replacement therapy.
Special Instructions
Not provided.
Limitations
Administration of iodine‑based contrast media and iodine‑containing drugs (e.g., amiodarone) can yield elevated results. Interference from gadolinium‑ or iodine‑containing contrast media for at least 96 hours post‑administration. Only based on ICP‑MS performance characteristics in a CLIA‑compliant Mayo Clinic lab; not FDA cleared.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
Iodine Concentration
Analyte
LOINC Codes
- 2492-7 - Iodine 24h Ur-mRate
- 2492-7 - Iodine 24h Ur-mRate
- 13362-9 - Specimen collect Time Ur
- 3167-4 - Specimen vol 24h Ur
- 26842-5 - Iodine 24h Ur-mCnc
- 77202-0 - Laboratory comment Report
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
10 mL
Minimum Volume
0.3 mL
Container
Clean plastic aliquot container or 10‑mL plastic urine tube; no metal cap or glued insert
Collection Instructions
Collect urine for 24 hours; refrigerate within 4 hours of completion; if using with (131)I uptake, begin after dose, discard prior void, include last void.
Patient Preparation
Avoid specimen collection for 96 hours after administration of gadolinium‑ or iodine‑containing contrast media.
Storage Instructions
Refrigerate within 4 hours of collection; submission refrigerated preferred.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | OK up to 28 days |
| Refrigerated | Preferred up to 28 days |
| Frozen | OK up to 28 days |