Isocyanate MDI, IgE, Serum
Use
The test is used for establishing a diagnosis of allergy to isocyanate MDI. It helps in defining the allergen responsible for eliciting signs and symptoms, identifying allergens responsible for allergic responses or anaphylactic episodes, confirming sensitization prior to starting immunotherapy, and investigating the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
If not ordering electronically, the Allergen Test Request form (T236) should be completed, printed, and sent with the specimen.
Limitations
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend on identification of allergen specificity. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 7430-2
- 7430-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
For 1 allergen: 0.3 mL; For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |