JC Virus DNA, PCR, Cerebrospinal Fluid
Also known as: John Cunningham Virus, Polyomavirus
Use
Aid in the diagnosis of infections caused by JC virus
Special Instructions
The test requires a volume of 0.5 mL of cerebrospinal fluid collected in a sterile container. The minimum volume required is 0.2 mL. Ensure proper sample storage as room temperature or refrigerated samples are stable for up to 7 days, and frozen samples remain stable for 90 days. Avoid contamination and ensure the integrity of the specimen to prevent rejection.
Limitations
This test was developed by LabCorp, and its performance characteristics were determined internally. It has not been cleared or approved by the FDA, as such clearance or approval is not deemed necessary by the FDA. The accuracy of detecting JC virus DNA through PCR may vary based on sample handling and storage conditions. Gross contamination, insufficient quantity, or specimen aging beyond recommended stability limits can impact test reliability.
Methodology
PCR-based (Real-time polymerase chain reaction (PCR))
Biomarkers
LOINC Codes
- 33295-7
- 33295-7
Result Turnaround Time
4-5 days
Related Documents
For more information, please review the documents below
Specimen
Cerebrospinal Fluid
Volume
0.5 mL
Minimum Volume
0.2 mL
Container
Sterile container for CSF
Storage Instructions
Room temperature or refrigerated for up to 7 days. Frozen up to 90 days.
Causes for Rejection
Quantity not sufficient for analysis; gross specimen contamination; specimen too old; leaking or broken tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 90 days |
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