Kaolin Clotting Time (KCT)
Use
The KCT is a sensitive screening test of lupus anticoagulants (LA) in patients with a history of thrombosis.6-10
Special Instructions
Not provided.
Limitations
The KCT may be prolonged in the presence of therapeutic plasma heparin or coagulation factor deficiencies (except factors VII and XIII). Platelet‑poor plasma must be used; platelet contamination impairs sensitivity for lupus anticoagulants. Additionally, no single assay can identify all lupus anticoagulants due to antibody heterogeneity.
Methodology
Clotting‑based (Other)
Biomarkers
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
Not provided
Container
Blue‑top (sodium citrate) tube
Collection Instructions
Collect citrated blood (blue‑top tube) by venipuncture, perform double centrifugation to obtain platelet‑poor plasma, transfer plasma into LabCorp PP transpak frozen purple tube (LabCorp No. 49482), freeze immediately and maintain frozen until tested.
Storage Instructions
Freeze immediately; sample should be frozen until testing.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Stable at room temperature up to four hours |
Other tests from different labs that may be relevant