Ki‑67
Use
Ki‑67 is a nuclear protein expressed in proliferating cells during late G1, S, G2, and M phases of the cell cycle, while quiescent (G0) cells do not express it. Increased Ki‑67 proliferative activity is associated with more aggressive tumors and decreased disease‑free survival. Computer‑assisted image analysis for Ki‑67 is validated only for breast cancer; for neuroendocrine/carcinoid tumors, use Ki‑67 NET; for other tumors, use Tech‑Only (stain only) Ki‑67.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
KI67
Protein
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
A formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred; or one unbaked, unstained slide for H&E staining (required) plus two to three positively charged unstained slides, cut at 4–5 microns, for each test/antibody ordered. Block and slide identifiers should exactly match requisition specimen ID.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. NYS clients please provide date and time of collection.