Casandra
Casandra Test Code NG38122Version 1 (DRAFT)
Performing Lab
KIT (c-KIT) Mutation Analysis
Also known as: c-KIT Mutation Analysis
Clinical Use
Order TestUse
The four tested exons encompass the majority of mutations found in gastrointestinal stromal tumors (GIST), melanoma, core-binding factor AML (CBF-AML), mast cell disease (systemic mastocytosis), and germ cell tumors. Mutation identification is useful for planning TKI therapy and predicting clinical course.
Special Instructions
Not provided.
Limitations
Do not use zinc fixatives. Block and slide identifiers should be clearly written and match exactly with the specimen ID and specimen labeling as noted on the requisition.
Test Details
New York Approved
Methodology
Sanger
Biomarkers
KIT
GeneSNVs + Indels
Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
7 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Bone Marrow
Volume
2 mL
Minimum Volume
Not provided
Container
EDTA tube
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.