Use

This test is useful for evaluating lymphocytoses of undetermined etiology, identifying B- and T-cell lymphoproliferative disorders involving blood and bone marrow, distinguishing acute lymphoblastic leukemia from acute myeloid leukemia (AML), and immunologic subtyping of acute leukemias. It aids in distinguishing reactive lymphocytes and lymphoid hyperplasia from malignant lymphoma, distinguishing between malignant lymphoma and acute leukemia, and phenotypic subclassification of B- and T-cell chronic lymphoproliferative disorders, including chronic lymphocytic leukemia, mantle cell lymphoma, and hairy cell leukemia. It also helps in recognizing AML with minimal morphologic or cytochemical evidence of differentiation and monoclonal plasma cells.