Lipid Panel With Apolipoprotein B (ApoB), GlycA (Inflammation), Diabetes Risk Index (DRI)

Casandra

Casandra Test Code LC58163Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 123567CPT Codes 0024, 80061, 81599, 82172

Lipid Panel With Apolipoprotein B (ApoB), GlycA (Inflammation), Diabetes Risk Index (DRI)

Clinical Use

Use

This "Extended Lipid Panel" quantifies the components of a typical lipid panel (TC, HDL-C and TG) along with ApoB by nuclear magnetic resonance (NMR) spectroscopy using the Vantera NMR Clinical Analyzer. Results from the Extended Lipid Panel Assay can be used by physicians to assist in CVD risk assessment. The principal protein component of LDL particles, ApoB, has been shown to be associated with CVD and is also an important CVD risk factor.

Special Instructions

Patient fasting is not required, but fasting for 12-14 hours is recommended for conditions where triglyceride values provide diagnostic information, such as screening for familial hypercholesterolemia or confirming hypertriglyceridemia.

Limitations

Triglyceride levels above 800 mg/dL will not allow LDL cholesterol calculation. GlycA measurements vary slightly depending on the type of specimen tube used, potentially leading to differences in results. GlycA is influenced by a variety of health conditions and should not be interpreted without a complete clinical history. DRI measurements from plasma specimens are typically 8 points lower than serum specimens. Hemolysis may reduce GlycA concentrations by more than 10%.

Test Details

Methodology

Mass Spectrometry

Biomarkers

8 targets

Apolipoprotein BCholesterol, TotalDiabetes Risk Index (DRI)GlycAHDL-CLDL-C (NIH Calc)Non-HDL CholesterolTriglycerides

LOINC Codes

Order Codes

2093-3
2571-8
2085-9
43396-1
13457-7
1884-6
82730-3
94560-0

Result Codes

2093-3
2571-8
2085-9
43396-1
13457-7
1884-6
82730-3
94560-0

Result Turnaround Time

1-3 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

Plain red-top tube

Collection Instructions

Collect specimen in plain red-top tube (no gel) and allow to clot upright at room temperature for 45 minutes. Centrifuge and transfer to a transport tube for storage at 2-8°C until shipped.