Lisdexamfetamine as Metabolite, Urine
Use
This test is used to detect the presence of Lisdexamfetamine as a metabolite in urine. Lisdexamfetamine is a prodrug that is metabolized into dextroamphetamine, a central nervous system stimulant. The test is important for monitoring compliance and therapeutic levels in patients prescribed with Vyvanse, as well as in toxicology testing for potential abuse or overdose situations. Accurate detection helps in the assessment of drug metabolism and pharmacokinetics in individuals.
Special Instructions
Ensure that the urine specimen is collected as a random sample without preservatives. Specimens must be refrigerated upon collection to ensure stability. It is crucial to submit one specimen per order as samples cannot be shared across multiple orders.
Limitations
The test is limited to the detection of Lisdexamfetamine as a metabolite in urine and does not measure other metabolites or compounds. It's sensitive to the concentration of the drug and may require re-sampling if the testing criteria are not met. The test method does not quantify the amount of drug present, only its presence or absence, which may necessitate additional testing for comprehensive toxicology results if needed.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 19346-6
- 19346-6
Result Turnaround Time
9-13 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
1 mL
Minimum Volume
0.2 mL
Container
Plastic preservative-free urine container
Collection Instructions
Collect 1 mL random urine specimen without preservative. Send specimen refrigerated in a plastic urine container.
Causes for Rejection
Thawing: Warm OK; Cold OK
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 180 days |
| Frozen | 180 days |