Casandra
Casandra Test Code QD21304Version 1 (DRAFT)
Performing Lab
Lynch Syndrome, PMS2 Sequencing and Deletion/Duplication
Also known as: HNPCC Mismatch Repair Gene Mutation, Hereditary Nonpolyposis Colon Cancer (HNPCC)
Clinical Use
Order TestUse
This test is used to identify individuals with Lynch syndrome (hereditary non‑polyposis colorectal cancer) through analysis of variants in the PMS2 gene, including sequencing and detection of deletions or duplications. Lynch syndrome is associated with increased risk of colorectal, endometrial and several other cancers; identification enables risk assessment and management planning.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
Not provided
Minimum Volume
2 mL
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