Manganese, Serum

Casandra

Casandra Test Code AR99585Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0099265CPT Code 83785

Also known as: MANG

Clinical Use

Order Test

Use

This test may be useful as a reasonable indicator of recent, active manganese exposure, providing a modest distinction between exposed and nonexposed individuals. It is not recommended for assessing manganese body stores. An alternative test, Manganese, Whole Blood, is recommended for monitoring potential manganese accumulation, especially in patients receiving total parenteral nutrition (TPN).

Special Instructions

Diet, medication, and nutritional supplements can introduce interfering substances. Patients should be advised to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications, upon the advice of their physician.

Limitations

Elevated results may be due to skin or collection-related contamination, including the use of noncertified metal-free collection/transport tubes. If contamination concerns exist due to elevated serum manganese levels, confirmation with a second specimen collected in a certified metal-free tube is recommended. Less than 5 percent of manganese in circulation is present in the serum, which may limit the test's accuracy for certain assessments.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

Manganese

Analyte

Concentration • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Result Codes

5683-8

Result Turnaround Time

1-3 days

Specimen

Serum

Volume

2 mL

Minimum Volume

0.5 mL

Container

ARUP Trace Element-Free Transport Tube

Collection Instructions

Separate from cells ASAP or within 2 hours of collection. Do not use utensils (i.e., syringes, needles) during sample transfer. Carefully pour directly into the transport tube, avoiding cellular components of blood.

Patient Preparation

Discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of a physician).

Causes for Rejection

Plasma specimens, specimens not separated from clot within 2 hours, specimens in separator tubes or Royal Blue (EDTA), specimens transported in unspecified tubes, hemolyzed specimens.