MaterniT21 Genome NO Gender
Use
The MaterniT Genome test provides comprehensive chromosome copy number analysis including unbalanced derivatives and, information about deletions or duplications of chromosome material 7 Mb or larger, as well as analysis of seven clinically relevant microdeletions less than 7 Mb in size.
Special Instructions
The following information must be provided with the test request form: patient's date of birth, gestational age, and additional patient demographic information: pregnancy type (singleton), donor egg status and the clinical indications including advanced maternal age and other indications. Samples must be shipped in a Sequenom collection kit to maintain integrity.
Limitations
While the results of these tests are highly accurate, discordant results may occur due to factors such as placental, maternal, or fetal mosaicism; prior maternal organ transplant; or maternal neoplasms. The test is not validated for multiple gestations and multifetal samples are excluded from processing. These are screening tests and should not replace prenatal diagnosis methods such as CVS or amniocentesis. Factors affecting the results include maternal BMI, systemic conditions like lupus, and certain pharmaceuticals. Results should be discussed with a qualified healthcare provider and should not be solely used for pregnancy management decisions.
Methodology
NGS
Biomarkers
LOINC Codes
- 53693-8
- 75605-6
- 75980-3
- 72486-4
- 75983-7
- 75558-7
- 73824-5
- 75570-2
- 79211-9
- 75578-5
- 92903-4
- 92899-4
- 92902-6
- 92900-0
- 75602-3
Result Turnaround Time
5-8 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
10 mL
Minimum Volume
5 mL
Container
Black-and-tan-top (Streck) tube
Collection Instructions
Only the Sequenom collection kit (PeopleSoft No. 116373) can be used for collection.
Storage Instructions
Room temperature. Do not refrigerate or freeze. Keep out of direct sunlight.
Causes for Rejection
Gestational age less than nine weeks; expired or incorrect blood tubes (including nonglass tubes); quantity not sufficient for analysis; received more than seven days from collections; excessive hemolysis; frozen specimens
Other tests from different labs that may be relevant