Casandra
Casandra Test Code NG54542Version 1 (DRAFT)
Performing Lab
MYC Amplification for Angiosarcoma
Also known as: c-MYC Amplification
Clinical Use
Order TestUse
Fluorescence in situ hybridization (FISH) testing for MYC gene amplification (8q24) assists in the diagnostic evaluation of angiosarcoma by detecting increased MYC copy number relative to centromere 8, providing evidence of amplification status.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Chromosome 8
ChromosomeCentromere 8 reference
Copy Number Alteration • Categorical (e.g., Positive / Negative / Indeterminate)
Unknown CNV
Copy Number RegionAmplification(s)
Copy Number Alteration • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Send paraffin block. Also send circled H&E slide for tech‑only (required). Cut slides: H&E slide (required) plus 4 unstained slides cut at 4‑5 microns. Circle H&E slide for tech‑only.
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen.