N-Telopeptide Cross-links (NTx), Urine

Casandra

Casandra Test Code LC55855Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 141093CPT Codes 82523, 82570

N-Telopeptide Cross-links (NTx), Urine

Also known as: Collagen Cross-linked N-Telopeptide, N-Telopeptide, NTx Test, Osteomark®

Clinical Use

Order Test

Use

Evaluation of osteoporosis and assessment of antiresorptive therapy

Special Instructions

Not provided.

Limitations

This test should not be used interchangeably with other biochemical markers of bone turnover or different assay methods for sequential patient monitoring. Due to the variability in results based on assay types, consistent use of a single method is recommended for reliable monitoring. Interpretation of results should be done considering the reference ranges specific to the patient population and the clinical context. Results could be influenced by non-standardized collection times and improper specimen handling or storage.

Test Details

Methodology

Immunoassay (ECLIA)

Biomarkers

Creatinine

Analyte

Creatinine

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

N-Telo/Creat. Ratio

Analyte

N-Telo/Creat. Ratio

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

N-Telopeptide

Analyte

N-Telopeptide

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Result Codes

27939-8 - Collagen NTx Ur-sCnc
2161-8 - Creat Ur-mCnc
14115-0 - Collagen NTx/Creat Ur-sRto

Result Turnaround Time

3-4 days

Specimen

Urine

Volume

20 mL

Minimum Volume

1 mL

Container

Plastic urine container without preservative

Collection Instructions

Collect a second void of the morning (no preservative). When monitoring therapy, baseline samples should be collected prior to initiation of therapy. Subsequent specimens should be collected at the same time of day as baseline specimens.