NT-proBNP
Also known as: proBNP, Propeptide of Brain Natriuretic Peptide
Use
This assay is used as an aid in the diagnosis of individuals suspected of having congestive heart failure. The test is further indicated for the risk stratification of patients with acute coronary syndrome and congestive heart failure. The test may also serve as an aid in the assessment of increased risk of cardiovascular events and mortality in patients at risk for heart failure who have stable coronary artery disease.
Special Instructions
Not provided.
Limitations
NT-proBNP values should be assessed in conjunction with other cardiovascular risk factors and clinical findings. Interpreting results in the setting of comorbidities such as cardiac, pulmonary, and renal disease, which are likely to increase natriuretic peptides above current thresholds for HF, should be done with caution. The accuracy of natriuretic peptides for the detection of HF is reduced in the setting of atrial fibrillation and sepsis, and careful interpretation is warranted.
Methodology
Immunoassay (ECLIA)
Biomarkers
NT-proBNP
Protein
LOINC Codes
- 33762-6
- 33762-6
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.7 mL
Container
Gel-barrier tube (preferred) or red-top tube
Collection Instructions
If a red-top tube is used, transfer separated serum to a plastic transport tube.
Storage Instructions
Room temperature
Causes for Rejection
Citrate plasma specimen; grossly hemolyzed samples; improper labeling
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 3 days |
| Refrigerated | 6 days |
| Frozen | 24 months |
Other tests from different labs that may be relevant