Opiate Confirmation, Meconium
Use
The test is aimed at detecting maternal prenatal opiate and opioid use up to 5 months before birth. Opiates are alkaloids derived from the opium poppy and show analgesic effects. They can cross the placenta and distribute into fetal tissues. This test particularly looks for the presence of opiates in meconium, the first fecal material passed by the neonate, indicating in utero exposure to drugs during the last months of pregnancy.
Special Instructions
Not provided.
Limitations
The test was developed by Mayo Clinic consistent with CLIA requirements and has not been cleared or approved by the FDA. Its performance characteristics have been determined by Mayo Clinic. The presence of interference or improper specimen collection can lead to diagnostic inaccuracies.
New York Approved
Methodology
Mass Spectrometry (LC-MS/MS)
Biomarkers
LOINC Codes
- 69026-3 - Opiates pnl Mec Cfm
- 69027-1 - Morphine Mec Cfm-mCnt
- 69028-9 - oxyMORphone Mec Cfm-mCnt
- 68541-2 - HYDROmorphone Mec Cfm-mCnt
- 68542-0 - Codeine Mec Cfm-mCnt
- 68543-8 - oxyCODONE Mec Cfm-mCnt
- 68544-6 - HYDROcodone Mec Cfm-mCnt
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Stool
Volume
1 g
Minimum Volume
0.3 g
Container
Stool container
Collection Instructions
Collect entire random meconium specimen.
Causes for Rejection
Grossly bloody; Diapers
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 28 days |
| Frozen | 28 days |