Opiates, Serum or Plasma, Quantitative
Also known as: OPIS SP
Use
This test is used for monitoring patient adherence to prescribed opiates. It quantifies the presence of specific opiates in serum or plasma to ensure that patients are taking their medications as prescribed. The test is not valid for forensic use due to the presence of common metabolites that can originate from various opiates, some of which may themselves be prescription drugs. The concentration value must be above the cutoff level to be considered positive.
Special Instructions
Not provided.
Limitations
Identification of specific drugs taken by the specimen donor can be problematic. Factors such as noncompliance, inappropriate timing, poor absorption, or testing limitations can lead to expected drugs not being detected. Drug identification is further complicated by common metabolites from multiple opiates. All drugs measured are in the non-glucuronidated (free) form. The test's performance characteristics have not been cleared or approved by the FDA.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3680-6 - HYDROcodone SerPl-mCnc
- 3683-0 - HYDROmorphone SerPl-mCnc
- 3506-3 - Codeine SerPl-mCnc
- 3827-3 - Morphine SerPl-mCnc
- 12788-6 - 6MAM SerPl-mCnc
- 3893-5 - oxyCODONE SerPl-mCnc
- 60467-8 - oxyMORphone SerPl-mCnc
Result Turnaround Time
1-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP standard transport tube
Collection Instructions
Separate serum or plasma from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Separator tubes, plasma or whole blood collected in light blue (sodium citrate) tubes, specimens exposed to repeated freeze/thaw cycles, hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 week |
| Refrigerated | 2 weeks |
| Frozen | 3 years |
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