Osteocalcin by Electrochemiluminescent Immunoassay

Casandra

Casandra Test Code AR04199Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0020728CPT Code 83937

Osteocalcin by Electrochemiluminescent Immunoassay

Also known as: OSTEO NMID

Clinical Use

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Use

The Osteocalcin by Electrochemiluminescent Immunoassay is primarily used to assess bone metabolism and turnover, which is critical in the diagnosis and management of osteoporosis and metabolic bone diseases. It measures the osteocalcin levels in the blood, which can provide insight into bone formation rates. This test is valuable for monitoring treatment efficacy in patients receiving therapy for osteoporosis. Abnormal levels may indicate metabolic bone disorders or problems with bone turnover.

Special Instructions

Ensure proper patient preparation and specimen collection as detailed in the test's guidelines to avoid delays in processing. Use serum separator tubes or EDTA tubes for collection, and follow specific handling instructions to maintain specimen integrity. This test has New York State approval, ensuring compliance for patients in New York.

Limitations

The test may not accurately reflect osteocalcin levels in patients with impaired renal function, as the osteocalcin result could be elevated due to impaired clearance or renal osteodystrophy. Pre-analytical variables such as sample handling and storage conditions can significantly affect test results, necessitating strict adherence to collection and processing instructions.

Test Details

FDA Approved

New York Approved

Methodology

Immunoassay (ECLIA)

Biomarkers

Osteocalcin

Protein

Osteocalcin • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

2697-1

Result Turnaround Time

0-1 days

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.3 mL

Container

ARUP standard transport tube

Collection Instructions

Allow serum tube to sit for 15-20 minutes at room temperature for proper clot formation. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection.