Pancreatic Amylase
Also known as: Amylase Fractionation, Isoamylase
Use
Evaluate pancreatic disease. Amylase is primarily produced in the pancreas and salivary glands. Isoenzymes may be used to determine the source of an elevated amylase concentration. Measurement of pancreatic amylase activity is of value in diagnosing pancreatitis and other pancreatic disorders which result in elevation of serum and urine amylase.
Special Instructions
Separate serum or plasma from cells within 30 minutes of collection. Hemolysis and the use of anticoagulants other than lithium heparin (such as Citrate and fluoride) inhibit the assay reaction and are causes for rejection.
Limitations
Patients with macroamylase may have elevated pancreatic amylase results. The elevation is due to the higher than normal level of pancreatic amylase in the macroimmune complex. This elevated pancreatic amylase is not diagnostic for pancreatitis, however, measurement of an elevated pancreatic amylase in urine is confirmatory of pancreatitis, pancreatic trauma, or pancreatic carcinoma since macroamylases are too large for renal clearance.
Methodology
Other
Biomarkers
LOINC Codes
- 1805-1
- 1805-1
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
1 mL
Container
Red-top tube, gel-barrier tube
Collection Instructions
Separate serum or plasma from cells within 30 minutes of collection.
Storage Instructions
Room temperature; stable for seven days. Stable refrigerated for one month.
Causes for Rejection
Hemolysis; use of anticoagulants other than lithium heparin (Citrate and fluoride inhibit the assay reaction.)
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 1 month |
Other tests from different labs that may be relevant