Parvovirus B19, Molecular Detection, PCR, Varies
Use
Parvovirus B19 is a DNA virus that preferentially replicates in erythroid progenitor cells. Infection with parvovirus B19 can occur at any age but is most common early in life. The virus is transmitted by respiratory secretions, and occasionally by blood products. Parvovirus B19 infections can be asymptomatic or produce a wide spectrum of diseases ranging from erythema infectiosum (“fifth disease” characterized by a classic “slapped cheek” rash) to arthropathy and severe anemia, depending on the host's immune competence. In pregnant women, it may cause hydrops fetalis, congenital anemia, spontaneous abortion, or stillbirth.
Special Instructions
Specimen source is required. If not ordering electronically, complete and send a Microbiology Test Request (T244) with the specimen.
Limitations
A negative result does not necessarily indicate the absence of parvovirus B19 infection due to the virus potentially being present at levels below the detection limit or due to inhibitory substances in the specimen. The test only detects genotype 1 parvovirus B19, with its ability to detect genotypes 2 and 3 unknown. Results are qualitative and should be close to the clinical presentation of the patient.
New York Approved
Methodology
PCR-based (qPCR)
Biomarkers
LOINC Codes
- 9571-1
- 9571-1
- 31208-2
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Amniotic Fluid
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Amniotic fluid container
Collection Instructions
Do not centrifuge. Label specimen as amniotic fluid.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 7 days |