Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Spinal Fluid

Casandra

Casandra Test Code MC85297Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID 605130

Pediatric Autoimmune Encephalopathy/CNS Disorder Evaluation, Spinal Fluid

Clinical Use

Use

Autoimmune encephalitis and myelitis are increasingly recognized as causes of central nervous system diseases in children and adolescents. Timely diagnosis and identification of specific antibodies can guide treatment strategies and improve outcomes. Disorders associated with antibodies such as NMDA-R, aquaporin-4, CASPR2, GFAP, and others are included in evaluations, providing crucial diagnostic clarity.

Special Instructions

When multiple evaluations are ordered on the same order number, duplicates are canceled. This ensures efficient resource utilization and avoids redundant testing.

Limitations

Negative results do not exclude a diagnosis of autoimmune CNS disorders. Diagnostic accuracy can be influenced by sample quality, timing of sample collection relative to disease course, and technical factors inherent to the assays utilized.

Test Details

New York Approved