Perampanel Quantitative, Serum or Plasma
Also known as: PERAMP
Use
The Perampanel Quantitative, Serum or Plasma test is used to optimize drug therapy and monitor patient adherence by measuring the concentration of perampanel, an antiepileptic drug. Perampanel is used for the treatment of partial-onset seizures and primary generalized tonic-clonic seizures. Measuring its levels in serum or plasma helps ensure therapeutic drug concentrations and minimizes the risk of adverse effects.
Special Instructions
The test is performed by a non-ARUP laboratory, specifically NMS Labs. Separate specimens must be submitted for this test when multiple tests are ordered. It is important to prepare the specimen by separating it from cells as soon as possible or within 2 hours of collection. The minimum volume required is 0.3 mL and the sample should be transferred to an ARUP Standard Transport Tube.
Limitations
The test is not performed at ARUP, which requires separate specimens for multiple test orders. Performed by NMS Labs, the test has not been cleared or approved by the US FDA. Variations in patient metabolism, compliance, and drug interactions may affect the perampanel levels, requiring interpretation of results within the clinical context. Use of separator tubes is not acceptable for this test.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma.
Causes for Rejection
Separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 month |
| Refrigerated | 1 month |
| Frozen | 25 months |
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