Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G Polymorphism
Use
The Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G Polymorphism test evaluates the genetic polymorphism of the PAI-1 gene. This polymorphism has been associated with various thrombotic disorders and can influence the regulation of fibrinolysis. Identifying the 4G/5G polymorphism in patients can provide critical information about their genetic predisposition to thrombotic events, potentially guiding treatment and prevention strategies for thrombotic conditions.
Special Instructions
New York clients must ensure informed consent is obtained and documented on the request form or electronic order. The test involves PCR and RFLP technologies to determine the genotype, which helps in the assessment of genetic predisposition to certain conditions.
Limitations
Results are for investigational purposes only and should not be used as the sole diagnostic procedure without confirmation by another medically established diagnostic product or procedure. Specimen handling and improper collection might affect test results. Therefore, following proper specimen collection and handling procedures is crucial for accurate results.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 52757-2
- 77202-0
Result Turnaround Time
7-14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
1 mL
Container
Lavender top (EDTA) or yellow top (ACD)
Collection Instructions
Invert several times to mix blood. Send whole blood specimen in original tube. Send refrigerate.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 days |
| Refrigerated | 8 days |