Poliovirus (Types 1, 3) Antibodies
Also known as: POLIO AB
Use
The Poliovirus (Types 1, 3) Antibodies test detects neutralizing antibodies to poliovirus types 1 and 3. The presence of these antibodies implies immunity, which may represent prior immunization or current or past infection. The test is serotype specific, meaning antibodies against one type do not confer immunity against the other type. This test provides valuable information about a patient's immunization status against poliovirus, helping in assessing protection levels or exposure history.
Special Instructions
Not provided.
Limitations
The serum neutralization test used in detecting poliovirus antibodies is limited to serotype specificity; antibodies detected for one type do not indicate immunity to the other. The test requires careful specimen handling to avoid contamination and degradation. Unacceptable conditions include plasma specimens, and those that are contaminated, hemolyzed, or severely lipemic. Additionally, stability of the specimen must be maintained at specific temperatures; ambient stability is limited to 48 hours, refrigerated up to two weeks, and frozen for up to one year. Repeated freeze/thaw cycles should be avoided to ensure accurate results.
New York Approved
Methodology
Immunoassay (Other)
Biomarkers
Polio Virus Antibody Type 1
AntibodyPolio Virus Antibody Type 3
Antibody
LOINC Codes
- 5281-1 - PV1 NAb Titr Ser Nt
- 5285-2 - PV3 NAb Titr Ser Nt
Result Turnaround Time
6-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Causes for Rejection
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
Other tests from different labs that may be relevant