Prenatal Noonan Spectrum Disorders Panel
Use
Panel to evaluate for prenatal diagnosis of Noonan spectrum disorders, a group of RASopathies associated with congenital anomalies and genetic syndromes in the fetus (e.g., Noonan syndrome, LEOPARD syndrome, cardio‑faciocutaneous, Costello syndrome, and related RAS‑MAPK pathway disorders). Useful when fetal anomalies are detected and targeted multi‑gene sequencing is indicated.
Special Instructions
Order via Prenatal Genetic Testing Requisition Form (Test Code 357). If sufficient fetal material, tests may be performed concurrently. Use standard submission forms supplied by GeneDx.
Limitations
Technical limitations not stated explicitly in rendered page—see GeneDx website for gene‑specific coverage and limitations (as noted in requisition form).
Methodology
NGS (Targeted)
Biomarkers
Result Turnaround Time
14-21 days
Related Documents
For more information, please review the documents below
Specimen
Tissue
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Submit fetal material sufficient to perform testing; see prenatal requisition form.
Other tests from different labs that may be relevant