Propoxyphene and Metabolite, Serum or Plasma
Also known as: PROPOX SP
Use
The Propoxyphene and Metabolite, Serum or Plasma test is significant for therapeutic drug monitoring and emergency toxicology as it helps in confirming propoxyphene exposure or drug adherence in patients. It is particularly useful for following up on presumptive results and ensuring the presence and quantitation of propoxyphene and its metabolites in serum or plasma.
Special Instructions
Amitriptyline is a known interference, which could impact test results. This test is not performed at ARUP, so separate specimens must be submitted when multiple tests are ordered. The test is performed by a non-ARUP laboratory and the performance characteristics were developed by NMS Labs.
Limitations
This test has not been cleared or approved by the US Food and Drug Administration, indicating potential regulatory limitations. The use of separator tubes is unacceptable for specimen submission, which could affect sample integrity. The test's performance is contingent upon conditions such as ambient stability (2 weeks), refrigerated stability (2 weeks), and frozen stability (3 months). Additionally, digital data review can occur remotely under CLIA regulations.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3543-6
- 10341-6
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.7 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate from cells within 2 hours. Transfer serum or plasma to an ARUP Standard Transport Tube.
Causes for Rejection
Separator tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 weeks |
| Refrigerated | 2 weeks |
| Frozen | 3 months |
Other tests from different labs that may be relevant