Prostate Specific Antigen, Free Percentage (Includes Free PSA and Total PSA)
Also known as: PSA FP
Use
The Prostate Specific Antigen, Free Percentage test helps distinguish prostate cancer from benign prostatic conditions in individuals aged 50 years and older who have a total PSA between 3 and 10 ng/mL and negative digital rectal examination findings. It is used to aid in determining the risk of prostate cancer in patients with mildly elevated PSA levels, but a biopsy is required for definitive diagnosis.
Special Instructions
This test is not suitable for initial prostate cancer screening. The preferred initial test is Prostate Specific Antigen, Total (0070121) combined with a digital rectal exam. Values obtained with different assay methods should not be used interchangeably.
Limitations
Prostatic biopsy is necessary for the diagnosis of cancer. While the test can suggest the risk of prostate cancer, elevated PSA levels can also be due to benign prostatic hyperplasia or inflammatory conditions. Results obtained from this test should not be exclusively used in clinical decision-making without considering other clinical factors.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ECLIA)
Biomarkers
LOINC Codes
- 83112-3
- 10886-0
- 12841-3
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
Serum separator tube
Collection Instructions
Collect serum. Also acceptable: Green (lithium heparin), Lavender (K2EDTA), or Pink (K2EDTA). Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer to an ARUP Standard Transport Tube.
Storage Instructions
Frozen
Causes for Rejection
Grossly hemolyzed specimens. Vaginal washings.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 5 days |
| Frozen | 3 months |
Other tests from different labs that may be relevant