Prothrombin Time Mix 1:1, Plasma
Use
This test is used as a screening tool to detect a deficiency of one or more clotting factors of the extrinsic coagulation system due to hereditary deficiency or acquired conditions such as liver disease, vitamin K deficiency, or a specific factor inhibitor. It helps in determining the cause of a prolonged prothrombin time by distinguishing factor deficiencies from factor inhibitors.
Special Instructions
This test is only orderable as a reflex. Heparin or Coumadin therapy should be noted when ordering the test.
Limitations
Prothrombin time (PT) mixing studies have no utility when the patient PT is normal. Lipemic specimens may interfere with the instrument clot detection mechanism, potentially affecting the test results.
New York Approved
Methodology
Automated Analyzer (Coagulation)
Biomarkers
LOINC Codes
- 5959-2
- 5959-2
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
Not provided
Minimum Volume
Not provided
Container
Plasma Na Cit
Collection Instructions
Collect plasma in a Plasma Na Cit tube and freeze within 14 days.
Patient Preparation
Heparin or Coumadin therapy should be noted.
Storage Instructions
Keep frozen for up to 14 days.
Causes for Rejection
Gross hemolysis, gross lipemia, and gross icterus specimens should be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 14 days |