Rivaroxaban
Also known as: Xarelto®
Use
Measurement of drug level in order to monitor therapeutic level and/or diagnose under-dosage or potential toxicity
Special Instructions
Not provided.
Limitations
This test has not been cleared or approved by the FDA, and there can be increased exposure and reduced clearance in cases of significant renal and hepatic impairment. Direct interactions with cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) affecting metabolism may alter drug levels, impacting efficacy and safety.
Methodology
Mass Spectrometry
Biomarkers
Rivaroxaban
Analyte
LOINC Codes
- 72624-0
- 72624-0
Result Turnaround Time
5-7 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.5 mL
Container
Blue-top (citrate) tube (preferred), lavender-top (EDTA) tube, or green-top (heparin) tube
Collection Instructions
Transfer plasma to a plastic transport tube.
Storage Instructions
Room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
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