Saccharomyces cerevisiae Antibody, IgA, Serum
Use
The Saccharomyces cerevisiae Antibody, IgA test is useful for measuring IgA anti-Saccharomyces cerevisiae antibodies, aiding in distinguishing between ulcerative colitis and Crohn disease in patients where the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations. This test is not designed to determine the extent of the disease in patients with inflammatory bowel disease or to assess the response to disease-specific therapies such as surgical resection of diseased intestine.
Special Instructions
This test should only be used in conjunction with other diagnostic methods. It should not be solely relied upon to establish the diagnosis of ulcerative colitis or Crohn disease or to differentiate between them. Testing should be complemented by assessing antineutrophil cytoplasmic antibodies (ANCA).
Limitations
The test should not be used as a standalone diagnostic tool for ulcerative colitis or Crohn disease. Some patients with Crohn disease may have detectable ANCA, and some patients with ulcerative colitis may have detectable IgA and/or IgG ASCA. Additionally, some patients with ulcerative colitis or Crohn disease may not have detectable ANCA, IgA ASCA, or IgG ASCA. Therefore, results should be interpreted in the context of the overall clinical evaluation including other diagnostic tests.
New York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 47320-7
- 47320-7
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial. Collect using a serum gel or red top tube.
Causes for Rejection
Gross hemolysis, gross lipemia, and heat-treated specimens will be rejected. Gross icterus is acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 21 days |
| Frozen | 21 days |