Casandra
Casandra Test Code QD87382Version 1 (DRAFT)
Performing Lab
Sirolimus, LC/MS/MS
Also known as: Rapamycin, Rapamune®
Clinical Use
Order TestUse
Sirolimus is an immunosuppressant drug used to prevent organ graft rejection. Therapeutic drug monitoring is used to optimize dose and avoid toxicity. Peak concentrations are reached in 2 hours following oral administration. Elimination half‑life in males is approximately 72 hours; in females approximately 61 hours.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
Mass Spectrometry
Biomarkers
Sirolimus
AnalyteSirolimus, LC/MS/MS
Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
LOINC Codes
Result Codes
- 29247‑4
Result Turnaround Time
1-2 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
2 mL (1 mL minimum)
Minimum Volume
1 mL
Container
EDTA (lavender‑top) tube
Collection Instructions
Collect specimen 1 hour prior to next dose (12 hour trough)
Causes for Rejection
Clotted
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 5 days |
| Refrigerated | 7 days |
| Frozen | 30 days |
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