T-Cell Subsets, Regulatory (Tregs), Blood

Casandra

Casandra Test Code MC35448Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID TREGSCPT Codes 86359, 86361

T-Cell Subsets, Regulatory (Tregs), Blood

Clinical Use

Use

The T-Cell Subsets, Regulatory (Tregs), Blood test is crucial for evaluating patients with clinical features of IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked inheritance) and other primary immunodeficiencies. It is also useful in autoimmune diseases, allergy and asthma, and monitoring graft-vs-host disease post-hematopoietic stem cell transplantation. This test helps in understanding the regulatory T cells (Tregs) role in suppressing aberrant immune responses.

Special Instructions

Not provided.

Limitations

This test provides only quantitative information on various regulatory T cell (Treg) subsets and does not provide functional information about these populations. Molecular testing is needed to confirm a diagnosis of IPEX. The timing and consistency of blood collection are critical for monitoring lymphocyte subsets serially.

Test Details