Thallium/Creatinine Ratio, Random, Urine

Casandra

Casandra Test Code MC61989Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID TLUCRCPT Codes 82570, 83018

Thallium/Creatinine Ratio, Random, Urine

Clinical Use

Use

Detecting toxic thallium exposure in random urine specimen. Thallium is odorless, tasteless, and found in trace amounts in the earth's crust, used in electronic manufacturing and previously in rodenticides. Exposure may occur via ingestion (food, smoking). Acute ingestion can lead to vomiting, diarrhea, sensorimotor polyneuropathy, and alopecia within about a week; other symptoms include gastrointestinal, myalgia, hypertension, cardiac, and liver injury. Most thallium is excreted in urine, detectable as early as one hour post exposure and up to two months thereafter.

Special Instructions

For specimen collection: if gadolinium- or iodine-containing contrast media has been administered, do not collect a specimen for 96 hours. Use clean plastic urine collection container with no metal cap or glued insert; supplies include Urine Tubes, 10 mL (T068). Submission in plastic 10‑mL urine tube or a clean plastic aliquot container with no metal cap or glued insert. Refer to 'Metals Analysis Specimen Collection and Transport' for complete instructions.

Limitations

No significant cautionary statements were provided regarding analytical or interpretive limitations.

Test Details

New York Approved

Methodology

Mass Spectrometry (ICP‑MS)

Biomarkers

2 components

Thallium Measurement (TLUC) • ICP‑MSCreatinine Measurement (CRETR) • Clinical Chemistry

LOINC Codes

Order Codes

13469-2

Result Codes

2161-8
13469-2

Result Turnaround Time

2-5 days

Specimen

Urine

Volume

7 mL

Minimum Volume

1.3mL

Container

Clean, plastic urine collection container with no metal cap or glued insert; submission container: plastic, 10‑mL urine tube or clean plastic aliquot container with no metal cap or glued insert