Casandra
Casandra Test Code QD56226Version 1 (DRAFT)
Performing Lab
Thrombophilia DNA Mutation Analysis
Clinical Use
Order TestUse
This test includes analysis for two specific mutations associated with hereditary thrombophilia: Factor V Leiden and the Prothrombin (Factor II) 20210G>A mutation. These variants are known to increase the risk of thromboembolism. Detection of one or both variants informs genetic risk assessment in individuals with personal or family history of thrombosis.
Special Instructions
Not provided.
Limitations
Not provided.
Test Details
Methodology
PCR-based (PCR)
Biomarkers
F5, F2
GeneSNV/Indel • Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
5-6 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
3 mL
Container
Lavender (EDTA) tube; also acceptable: royal blue-top EDTA tube, sodium heparin (dark green-top) tube, ACD solution A/B (yellow-top) tube, lithium heparin (dark green-top) tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 days |
| Refrigerated | 8 days |
| Frozen | 30 days |
Related Tests
Other tests from different labs that may be relevant
Thrombotic Risk, DNA Panel
ARUP Laboratories
Factor II (Prothrombin), DNA Analysis
Labcorp
Prothrombin G20210A Mutation, Blood
Mayo Clinic Lab
Factor V Leiden (F5) R506Q Mutation
ARUP Laboratories
Invitae Hereditary Thrombophilia Panel
Invitae Corporation
Factor V Leiden (R506Q) Mutation, Blood
Mayo Clinic Lab
Prothrombin (F2) c.*97G>A (G20210A) Pathogenic Variant
ARUP Laboratories
Factor V Leiden Mutation Analysis
Labcorp
Factor V R2 DNA Analysis
Labcorp
Thrombosis Disorders, Comprehensive Gene Panel, Next-Generation Sequencing, Varies
Mayo Clinic Lab