Titanium Quantitative, Serum or Plasma
Also known as: TITANIU SP
Use
Titanium quantitative testing in serum or plasma is useful in the assessment of patients with possible titanium exposure. It is significant in monitoring patients who have titanium-based implants such as prostheses, where elevated levels may indicate wear. However, the test cannot predict prosthesis failure based on titanium concentration alone. Elevated levels could also be due to environmental contamination, so unexpected elevated results should be reconfirmed with specimens collected using trace metal-free containers.
Special Instructions
This test is not performed at ARUP Laboratories. Each test requires separate sample submissions if multiple tests are ordered. The testing is conducted by NMS Labs, and specimens should be transferred to acid-washed vials or ARUP transport tubes.
Limitations
Results may be affected by environmental contamination during specimen collection. Certified metal-free containers are recommended for accurate measurement. It is also noted that elevated titanium concentrations alone do not necessarily indicate prosthesis wear or failure, necessitating clinical correlation and possibly further testing.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 8244-6
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.6 mL
Container
acid-washed transfer vial or ARUP transport tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated. Also acceptable: Room temperature or frozen.
Causes for Rejection
Separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 month |
| Refrigerated | 1 month |
| Frozen | 1 month |
Other tests from different labs that may be relevant