Toxocara Antibody, IgG, Serum
Use
Toxocariasis is a zoonotic parasitic disease caused by the nematode, Toxocara, which primarily affects dogs and cats but can lead to infection in humans through ingestion of contaminated material containing Toxocara eggs. Diagnosis relies on antibody detection, as humans do not excrete eggs. This test aids in the diagnosis of Toxocara infection by detecting IgG antibodies to Toxocara species, helping to identify past or present infection. It is particularly relevant for individuals at higher risk, such as children, adolescents, and dog owners.
Special Instructions
Not provided.
Limitations
A single negative result does not exclude infection, particularly in cases of low parasitic burden or ocular toxocariasis where antibody levels might be low. False-negative results can occur in immunosuppressed individuals. False-positive results may arise due to other helminth infections. This test cannot differentiate between current and past infections, as measurable titers do not indicate the stage of infection.
Methodology
Immunoassay (ELISA)
Biomarkers
Toxocara IgG
Protein
LOINC Codes
- 40674-4 - T canis IgG Ser Ql IA
- 40674-4 - T canis IgG Ser Ql IA
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Storage Instructions
Prefer frozen for 30 days, or refrigerated for up to 5 days.
Causes for Rejection
Gross hemolysis, gross lipemia, heat-inactivated samples are rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 5 days |
| Frozen | 30 days |
