Trisomy 12
Use
FISH test on hematologic specimens for detection of Trisomy 12. Trisomy 12 is a common recurring chromosomal defect in chronic lymphocytic leukemia (CLL). It has been reported in 15–30% of cases and is correlated with atypical morphology.
Special Instructions
Not provided.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract. Specimens are subject to rejection if they are clotted, exposed to extreme temperatures, contain anticoagulants toxic to cells, or have an insufficient number of cells.
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Chromosome 12
Chromosome
Result Turnaround Time
5 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
Not provided
Container
EDTA preferred (NaHep accepted)
Storage Instructions
2°C to 25°C
Causes for Rejection
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |