Special Instructions

A hereditary cancer clinical questionnaire must accompany all submitted specimens. To facilitate collection, Oragene Dx 500 saliva collection kits can be procured via PeopleSoft No. 87917 at local Labcorp branches. Additionally, coordination with CMBP genetic services is recommended for testing inquiries and setup. For saliva samples, patients should refrain from eating, drinking, smoking, or chewing gum 30 minutes prior to collection.

Limitations

The VistaSeq® RET analysis is unable to detect variants in noncoding or deep intronic regions, and may not reliably detect microsatellite repeats, mosaic variants, or genomic rearrangements such as transposable elements or inversions. Copy number analysis could miss some partial exon rearrangements and the presence of pseudogenes might affect the detection of variants in specific genes. The assay is not intended for detecting somatic mutations, and bone marrow transplants might impact outcomes. Interpretations should be clinically correlated considering potential interactions of variants across different genes and hereditary syndrome causes not covered by this test.

Biomarkers

LOINC Codes

Result Turnaround Time

Related Documents

Stability Requirements