Casandra
Casandra Test Code QD81118Version 1 (DRAFT)
Performing Lab
Lab Quest DiagnosticsLab Test ID 934
VMA (Vanillylmandelic Acid), 24‑Hour Urine without Creatinine
Also known as: VMA, VMA, 24hr Urine
Clinical Use
Order TestUse
Measurement of vanillylmandelic acid (VMA) in a 24‑hour urine collection is used for detection and monitoring of catecholamine‑secreting tumors such as neuroblastoma and occasionally pheochromocytoma. Elevated levels may suggest such tumors, though additional confirmatory testing is required.
Special Instructions
Not provided.
Limitations
Elevated VMA alone is not diagnostic; up to 20‑32% of neuroblastoma patients may not have elevated VMA. VMA is not the preferred analyte for pheochromocytoma (metanephrines are more sensitive).
Test Details
Methodology
Mass Spectrometry
Biomarkers
Vanillylmandelic Acid (VMA)
AnalyteVMA, 24 hr Urine
Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Urine
Volume
Not provided
Minimum Volume
Not provided
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