Wheat, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to wheat and defining the allergen responsible for eliciting signs and symptoms. It can identify allergens responsible for allergic responses and/or anaphylactic episodes and confirm sensitization prior to beginning immunotherapy. The test can also investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. However, testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in cases where medical management does not rely on identifying allergen specificity.
Special Instructions
For a listing of all allergens available for testing, see the Allergens - Immunoglobulin E (IgE) Antibodies PDF. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may exhibit measurable levels of IgE antibodies in serum, and test results must be interpreted in the clinical context. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 6276-0
- 6276-0
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen; (0.05 mL x number of allergens) + 0.25 mL deadspace for more than 1 allergen
Container
Preferred: Serum gel; Acceptable: Red top; Submission: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
None related to predefined conditions.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |