Casandra
Casandra Test Code AL24039Version 1 (DRAFT)
Performing Lab
Lab AllelicaLab Test ID N/A
AbsoluteDx CAD
Clinical Use
Order TestUse
The AbsoluteDx CAD test identifies carriers of pathogenic mutations linked to familial hypercholesterolemia. It modulates penetrance through a Multi-Ancestry CAD PRS, offering precise risk estimations in Coronary Artery Disease (CAD).
Special Instructions
Test is ordered through Allelica's platform. Collection kits can be used in-clinic or shipped for at-home sampling. Saliva samples collected are utilized for DNA extraction.
Limitations
Limitations are contingent on the accuracy of polygenic and monogenic risk interpretations and potential disparities based on ancestry data alignment.
Test Details
Methodology
NGS (WGS)
Biomarkers
Sequencing combines low-coverage WGS and high-depth WES for comprehensive variant analysis.
Mutation (4 genes)
LDLRAPOBPCSK9LDLRAP1
Result Turnaround Time
3-4 weeks
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Saliva
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Saliva sample collected and shipped for processing