(1,3)-Beta-D-Glucan (Fungitell)
Also known as: BDGLUCAN
Use
The Fungitell test aids in the presumptive diagnosis of invasive or disseminated fungal infections, particularly those caused by P. jirovecii, Aspergillus, or Candida. It should be utilized in conjunction with other diagnostic procedures due to limitations in its detection capabilities. The test does not detect certain fungi such as Cryptococcus, which produce very low levels of (1,3)-beta-D-glucan, and will not detect zygomycetes like Absidia, Mucor, and Rhizopus, which do not produce (1,3)-beta-D-glucan.
Special Instructions
Reference ranges for pediatric patients (under 18 years old) have not been established, and assay ranges were validated in adult subjects. Ensure specimen separation from cells as soon as possible or within 2 hours of collection. Transfer serum to an ARUP Sterile Transport Tube for transport.
Limitations
The test may not detect the yeast phase of Blastomyces dermatitidis due to low production of (1,3)-beta-D-glucan. Additionally, it does not detect Cryptococcus or zygomycetes such as Absidia, Mucor, and Rhizopus, due to their lack of (1,3)-beta-D-glucan production. It is crucial to use this test in combination with other diagnostic methods to confirm fungal infection.
FDA ApprovedNew York Approved
Methodology
Automated Analyzer (Clinical Chemistry)
Biomarkers
LOINC Codes
- 93479-4
- 42176-8
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.5 mL
Container
ARUP Sterile Transport Tube
Collection Instructions
Separate from cells as soon as possible or within 2 hours of collection. Transfer serum to ARUP Sterile Transport Tube.
Storage Instructions
Refrigerated transport is required.
Causes for Rejection
Specimen types other than serum. Hemolyzed, icteric, or lipemic specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 2 weeks |
| Frozen | 2 weeks |