17-Hydroxypregnenolone Baseline Specimen
Also known as: OHPRGNBASE
Use
This test measures the level of 17-Hydroxypregnenolone in the blood, which is useful in assessing adrenal and gonadal function and for the diagnosis and management of disorders related to these glands, such as congenital adrenal hyperplasia (CAH) and other steroidogenic disorders. It can help in the differential diagnosis of hyperandrogenism and in monitoring therapy for certain endocrine disorders.
Special Instructions
It is necessary to ensure proper preparation of the specimen to maintain its stability. Serum or plasma must be separated from cells as soon as possible, ideally within 2 hours of collection, and then frozen immediately. This procedure is crucial for obtaining accurate test results.
Limitations
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration, which might limit its use in regulatory contexts. Results should be interpreted in conjunction with other clinical and laboratory data. Improper handling of specimens such as delays in freezing may lead to erroneous results.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 51670-8
- 51670-8
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.25 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer to an ARUP Standard Transport Tube and freeze immediately.
Storage Instructions
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Causes for Rejection
Refrigerated or room temperature specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 6 months |
