17‑Hydroxypregnenolone
Use
17‑Hydroxypregnenolone measurement is useful in evaluating congenital adrenal hyperplasia, including 3‑beta‑hydroxysteroid dehydrogenase deficiency and 17‑hydroxylase (P450c17) deficiency, as well as in assessment of women with hirsutism or infertility, as an ancillary steroid assay in comprehensive steroid‐related diagnostic panels.
Special Instructions
Not provided.
Limitations
Infants with 21‑hydroxylase deficiency may present with non‑elevated results, potentially impairing diagnostic interpretation in that population.
Methodology
Mass Spectrometry
Biomarkers
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
2 mL
Minimum Volume
0.4 mL
Container
Red‑top tube (no gel)
Causes for Rejection
Gross hemolysis • Gross lipemia • Gross icterus • Serum separator tubes (SST) • Received at room temperature
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 5 days |
| Frozen | 28 days |
Other tests from different labs that may be relevant