17-Ketosteroids, Urine
Also known as: 17 KETO
Use
This test is used to assess adrenal androgen production by measuring the level of 17-ketosteroids in urine. It is often employed in evaluating disorders related to abnormal androgen production, and in particular, adrenal function. The test is valuable in diagnosing conditions such as congenital adrenal hyperplasia, adrenal tumors, and Cushing's syndrome.
Special Instructions
An alternative and more specific test for adrenal androgen function is Dehydroepiandrosterone Sulfate, Serum (ARUP test code 0070040). Record total volume and collection time interval on the transport tube and test request form. Adequate refrigeration is crucial for specimen preservation.
Limitations
The test results may be impacted by a large number of substances, which can either falsely increase or decrease the levels of 17-ketosteroids. Medications and substances like carbamazepine, glucose, dexamethasone, spironolactone, among others, can interfere with the test results, causing inaccurate assessment of adrenal function. Therefore, care must be taken to account for potential interferences when interpreting results.
New York Approved
Methodology
Other
Biomarkers
LOINC Codes
- 35674-1
- 2162-6
- 21038-5
- 6766-0
- 19153-6
- 30211-7
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
24-hour collection
Minimum Volume
3 mL/aliquot
Container
ARUP Standard Transport Tubes
Collection Instructions
Refrigerate during collection. Transfer two 4 mL aliquots from a well-mixed 24-hour urine collection into ARUP Standard Transport Tubes or containing 20 mg Sulfamic Acid.
Storage Instructions
Refrigerated.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 4 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |