Aldosterone Inferior Vena Cava
Also known as: ALDO IVC
Use
This test is used to investigate primary and secondary aldosteronism through measurement of aldosterone levels in the inferior vena cava. It assists in diagnosing conditions related to aldosterone imbalance, such as primary aldosteronism, which can cause hypertension and other cardiovascular issues. Adrenal venous sampling is required to collect the specimen, making the test highly specific to assess aldosterone levels from the adrenal glands directly.
Special Instructions
For proper test execution, it is essential to adhere to the specified adrenal venous sampling procedure. Ensure that the specimen is processed and separated from cells as soon as possible or within two hours post collection to maintain integrity for analysis. Additional technical recommendations from the Endocrine Society regarding patient preparation, specimen collection, and medication management during testing should be consulted to avoid skewed results.
Limitations
False-positive or false-negative results may occur due to various factors, including patient preparation and improper specimen collection. Medications used for hypertension control can influence aldosterone levels, affecting the aldosterone-renin ratio (ARR), potentially leading to misinterpretation of results. It is crucial to ensure patient adherence to pre-test instructions and consult comprehensive guidelines to minimize risks of inaccurate outcomes.
New York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 92897-8
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Adrenal venous sampling procedure is required. Use Serum Separator Tube (SST) or Plain Red. Separate from cells as soon as possible or within 2 hours of collection.
Causes for Rejection
EDTA plasma
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 5 days |
| Frozen | 1 month |