Use

The Amphiphysin Antibody IgG, CSF test is primarily used in individuals with conditions such as stiff-person syndrome, paraneoplastic encephalomyelitis (PEM), and sensory neuronopathy (SN). It aids in the diagnosis of occult tumors, recurrence of tumors, or the presence of a second tumor. Amphiphysin antibodies are present in about 5 percent of patients with stiff-person syndrome and can be found variably in other paraneoplastic neurological syndromes (PNS). The antibody is closely associated with small-cell lung cancer and breast tumors.